Lumbar Intradiskal Platelet-Rich Plasma (PRP) Injections: A Prospective, Double-Blind, Randomized Controlled Study
Participants who received intradiskal PRP showed significant improvements in FRI, NRS Best Pain, and NASS patient satisfaction scores over 8 weeks compared with controls. Those who received PRP maintained significant improvements in FRI scores through at least 1 year of follow-up. Although
these results are promising, further studies are needed to define the subset of participants most
likely to respond to biologic intradiskal treatment and the ideal cellular characteristics of the intradiskal PRP injectate.
Effectiveness of Platelet-rich Plasma Injection for Rotator Cuff Tendinopathy: A Prospective Open-label Study.
A single intralesional injection of PRP under ultra-sound guidance resulted in a safe, significant, sustained improvement in pain, function, and MRI outcomes for participants with refractory RCT. This suggests that PRP has the potential to heal the muscle-tendon unit of the rotator cuff at the level of degenerative tissue and may be a primary nonsurgical treatment for refractory RCT. Randomized multidisciplinary effectiveness trials that add ultrasound and validated functional and imaging outcome measures are needed to further assess the effect of PRP for severe RCT compared to current therapy.
Short term results comparison of intraarticular platelet-rich plasma (prp) and
hyaluronic acid (ha) applications in early stage of knee osteoarthritis
In the PRP and HA groups, when pre-treatment KSS and VAS scores were compared with posttreatment three and six-month scores, a statistically significant difference was seen. When the groups were compared with each other, there was no significant difference between pre-treatment
KSS and VAS pain scores; however, a significant difference was found between post-treatment three and six-month scores.
In this study, the intra-articular PRP administration was more efficient than the HA administration in early knee osteoarthritis.
Treatment of Chronic Lateral Epicondylitis: Platelet Rich Plasma versus Extra-
Corporeal Shock Wave Therapy
Platelet rich plasma was proved to achieve superior results when compared to ESWT as regards pain
relief, improvement of elbow function and patient satisfaction at follow-up.